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phenobarbital will decrease the extent or effect of flurbiprofen by influencing hepatic enzyme CYP2C9/10 metabolism. Minimal/Importance Unidentified.phenobarbital will lessen the extent or result of piroxicam by influencing hepatic enzyme CYP2C9/10 metabolism. Insignificant/Significance Mysterious.Don't cease supplying Phenobarbital out of the blue